Assessment of coronary flow reserve with transthoracic Doppler echocardiography: comparison with intracoronary Doppler method.
10.3346/jkms.2000.15.2.139
- Author:
Soo Mi KIM
1
;
Wan Joo SHIM
;
Hong Euy LIM
;
Gyo Seung HWANG
;
Woo Hyuk SONG
;
Do Sun LIM
;
Young Hoon KIM
;
Hong Seog SEO
;
Dong Joo OH
;
Young Moo RO
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul
- Publication Type:Original Article ; Clinical Trial ; Comparative Study
- Keywords:
Coronary Artery Disease;
Echocardiography;
Ultrasonography, Doppler;
Circulation Coronary
- MeSH:
Adult;
Aged;
Blood Flow Velocity;
Comparative Study;
Coronary Angiography;
Coronary Circulation*;
Coronary Disease/ultrasonography*;
Echocardiography, Doppler/standards;
Echocardiography, Doppler/methods*;
Female;
Heart Rate;
Human;
Hyperemia/ultrasonography;
Linear Models;
Male;
Middle Age;
Prospective Studies;
Reproducibility of Results
- From:Journal of Korean Medical Science
2000;15(2):139-145
- CountryRepublic of Korea
- Language:English
-
Abstract:
To evaluate the feasibility and usefulness of transthoracic Doppler echocardiography (TTDE) as a non-invasive method in recording distal anterior descending (LAD) coronary flow velocity, we compared coronary flow reserve (CFR) measured by TTDE with measurements by intracoronary Doppler wire (ICDW). Twenty-one patients without LAD stenosis were studied. ICDW performed at baseline and after intracoronary injection of 18 microg adenosine. TTDE was performed at baseline and after intravenous adenosine (140 microg/kgmin for 2 min). Adequate Doppler recordings of coronary flow velocities during systole were obtained in 14 of 21 study patients (67%) and during diastole in 17 (81%) patients. Baseline and hyperemic peak diastolic flow velocities measured by TTDE were significantly smaller than those obtained by ICDW (p<0.05). However, diminishing trends of diastolic and systolic velocity ratio after hyperemia were similarly observed in both methods. CFR obtained by TTDE (3.0+/-0.5), was higher than the value calculated by ICDW (2.5+/-0.4). There were significant correlations between the values obtained by the two methods (r=0.72, p<0.01). It is concluded that TTDE is a feasible method in measuring coronary flow velocity and appears to be a promising non-invasive method in evaluating CFR.
