Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum.
10.3346/jkms.2000.15.2.229
- Author:
Youn Soo LEE
1
;
Chang Suk KANG
;
Byung Kee KIM
;
Sang In SHIM
Author Information
1. Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul. lys9908@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Lymphoma, T/NK-Cell;
Neoplasms,Sigmoid;
Gastrointestinal Neoplasms;
Diverticulum
- MeSH:
Antigens, CD56/analysis;
Case Report;
Colon/pathology*;
Colonic Neoplasms/radiography;
Colonic Neoplasms/pathology*;
DNA, Neoplasm/analysis;
Diagnosis, Differential;
Diverticulitis, Colonic/radiography;
Diverticulitis, Colonic/pathology*;
Human;
Immunoglobulins, Heavy-Chain/genetics;
Killer Cells, Natural/pathology*;
Killer Cells, Natural/chemistry;
Lymphoma, T-Cell/pathology*;
Lymphoma, T-Cell/chemistry;
Male;
Middle Age;
Necrosis;
Peritonitis/radiography;
Peritonitis/pathology;
Receptors, Antigen, T-Cell/genetics;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2000;15(2):229-232
- CountryRepublic of Korea
- Language:English
-
Abstract:
A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of involved bowel. Histologically, the intestinal wall showed diffuse infiltration of medium or large size lymphoma cells with angiocentric growth and necrosis. The lymphoma cells were CD56+, CD45RO+, CD3+, CD4-, CD8-, CD20-, and CD30- in paraffin sections with germline configuration of TCR-gamma gene, consistent with T/NK-cell lymphoma. Further staging revealed splenomegaly. Intestinal angiocentric T/NK cell lymphoma represents a distinct etiology of diverticulum with perforation.
