A case report of primary T-cell lymphoma of the liver.
10.3346/jkms.2000.15.2.240
- Author:
Hee Sung KIM
1
;
Young Hyeh KO
;
Howe J REE
Author Information
1. Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
- Publication Type:Case Report
- Keywords:
T-Cell Lymphoma;
Liver
- MeSH:
Case Report;
DNA, Neoplasm/analysis;
Female;
Gene Rearrangement;
Human;
Liver Neoplasms/radiography;
Liver Neoplasms/pathology*;
Liver Neoplasms/genetics;
Lymphoma, T-Cell/radiography;
Lymphoma, T-Cell/pathology*;
Lymphoma, T-Cell/genetics;
Middle Age;
Receptors, Antigen, T-Cell, gamma-delta/genetics;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2000;15(2):240-242
- CountryRepublic of Korea
- Language:English
-
Abstract:
The patient was a 50-year-old woman who presented intermittent mild fever with elevated liver enzymes for 12 years. The liver biopsy showed diffuse portal and sinusoidal involvement of lymphoid cells with minimal atypia and epithelioid histiocytic granuloma formation. Subsequent bone marrow biopsy showed lymphomatous involvement. The lymphocytes infiltrating the liver were reactive for T-cell marker and showed TCR gamma gene rearrangement. The patient was diagnosed as primary peripheral T-cell lymphoma of the liver. Indolent clinical course and resemblance with hepatitis were considered to be a rare and unique feature of this case.