Predictive Factors Associated with the Reversibility of Post-transplantation Diabetes Mellitus Following Liver Transplantation.
10.3346/jkms.2009.24.4.567
- Author:
Hwa Young AHN
1
;
Young Min CHO
;
Nam Joon YI
;
Kyung Suk SUH
;
Kuhn Uk LEE
;
Kyong Soo PARK
;
Seong Yeon KIM
;
Hong Kyu LEE
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ymchomd@snu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Diabetes Mellitus;
Liver Transplantation
- MeSH:
Adult;
Age Factors;
Diabetes Mellitus/diagnosis/*epidemiology;
Female;
Hepacivirus/isolation & purification;
Humans;
*Liver Transplantation;
Male;
Middle Aged;
Multivariate Analysis;
Mycophenolic Acid/analogs & derivatives/metabolism;
Predictive Value of Tests;
Prevalence;
Risk Factors
- From:Journal of Korean Medical Science
2009;24(4):567-570
- CountryRepublic of Korea
- Language:English
-
Abstract:
Post-transplantation diabetes mellitus (PTDM) is reversible in a considerable number of patients. We examined the prevalence and predictive factors of transient PTDM following liver transplantation. Forty-two of 74 PTDM patients showed the clinical features of transient PTDM. Compared with the persistent PTDM patients, they were characterized by younger age at the time of transplantation (49+/-7 vs. 53+/-8 yr, P<0.05), longer time before the development of PTDM (44+/-59 vs. 13+/-20 days, P<0.05), lower rate of hepatitis c virus seropositivity (0.0 vs. 9.4%, P<0.05), and use of mycophenolate mofetil (59.5 vs. 28.1%, P<0.05). Among these risk factors, age at the time of transplantation is the single independent predictive factor associated with the reversibility of PTDM.
