The post-TURP change of the serum electrolyte and osmolarity by preoperative administration of furosemide.
- Author:
Chang Dug HONG
1
;
Heon Chun LEE
;
Seong Un HWANG
;
Jae Sin PARK
;
Bong Il KIM
;
Kap Byung KIM
Author Information
1. Department of Urology, Taegu Catholic University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
TURP syndrome;
furosemide
- MeSH:
Furosemide*;
Heart Failure;
Humans;
Hyponatremia;
Osmolar Concentration*;
Potassium;
Sodium;
Transurethral Resection of Prostate
- From:Korean Journal of Urology
1992;33(6):1080-1085
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To see the effectiveness of preoperatively administered furosemide for preventing Hypo-osmolarity and hyponatremia during TURP, 30 patients undergoing TURP were followed every preoperatively, 30 min intra-operatively as well as immediate postoperatively, 6 hours and 24 hours postoperatively with measurements of serum sodium, serum potassium and serum osmolarity. Among the 30 patients, 15 patients (experimental group) were administered furosemide immediately before TURP, the other 15 patients (control group) were not administered. We compared the changes of serum sodium, serum potassium and osmolarity of experimental group with those of control group. The result showed that the serum sodium and serum osmolarity were decreased significantly (p<0.01) in control group, but were not decreased significantly in experimental group. Thus, the preoperatively administered furosemide may prevent the dilutional hyponatremia and hypo-osmolarity during TURP, and may be helpful in high risk patient such as congestive heart failure and poor renal function.