Clinical and Laboratory Findings of the 2012 Winter Seasonal Influenza A and B Outbreak at a Single Institution.
- Author:
Jae Won CHOI
;
Hyun Jun CHO
;
Hwang Min KIM
;
Seok HAHN
- Publication Type:Original Article
- Keywords:
Influenza;
Seasonal Influenza A;
Seasonal Influenza B
- MeSH:
Child;
Cough;
Fever;
Gangwon-do;
Humans;
Incidence;
Influenza, Human*;
Korea;
Medical Records;
Oseltamivir;
Pneumonia;
Retrospective Studies;
Seasons*
- From:Korean Journal of Pediatric Infectious Diseases
2014;21(1):1-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim for this study was to investigate clinical manifestation of seasonal influenza A and B during the 2012 winter season in Wonju, South Korea. Their clinical and laboratorial characteristics and effect of oseltamivir were compared and analyzed. METHODS: Children under the age of 18 years who visited the Wonju Severance Christian Hospital with fever or acute respiratory symptoms and who were diagnosed with influenza A or B by rapid antigen test from nasopharyngeal swab were selected for the study. The medical records of patients were retrospectively reviewed. RESULTS: Influenza A was detected in 374 patients (83.7%), and influenza B in 72 (16.6%). The incidence of influenza A was highest in February (n=186), while that of influenza B was highest in March (n=36). The most common symptoms were fever (n=434, 97.1%) and cough (n=362, 81.0%). No significant differences were observed between influenza A and B in symptoms and laboratory data. Patients who had used oseltamivir within 2 days showed statistically lower admission rate, shorter admission duration, and lower incidence of pneumonia. CONCLUSION: This study found no statistical difference between influenza A and B, in symptoms, progression, and laboratory test, but those who were treated with oseltamivir given within 2 days of the onset of fever experienced more positive outcomes.
