A Case of Esophageal Obstruction Complicated in a Patient with Chronic Granulomatous Disease: Esophageal obstruction in Chronic Granulomatous Disease.
- Author:
Ji Soo KIM
;
Jinsol HWANG
;
Young Hun CHOI
;
Woo Sun KIM
;
Joong Gon KIM
- Publication Type:Case Report
- Keywords:
Chronic granulomatous disease;
Esophageal stenosis;
Steroid
- MeSH:
Anti-Bacterial Agents;
Child;
Esophageal Stenosis;
Esophagus;
Granuloma;
Granulomatous Disease, Chronic*;
Humans;
Recurrence;
Steroids
- From:Korean Journal of Pediatric Infectious Diseases
2014;21(1):53-58
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chronic granulomatous disease (CGD) is an inherited immunodeficient disease characterized by recurrent infections and granuloma formation. Granulomatous obstruction of esophagus is one of the rare complications of CGD. The use of steroids and antimicrobials for esophageal obstruction by granuloma in CGD patients has been controversial due to the possibility of concomitant inapparent infection. We report a case of esophageal obstruction in an 8-year-old CGD patient showing the poor response to antibiotics therapy. However, dramatic improvement of symptoms and radiologic findings of esophageal obstruction were achieved after steroid therapy. One month after discontinuation of steroid, esophageal obstruction recurred and the patient was re-treated with steroid. After that time, he experienced one more recurrence of esophageal obstruction. This symptom subsided after antibiotics therapy without steroid and he has been followed up to the present without further relapse.
