A Case of Duodenal Obstruction Induced by the Short-term Use of a Nonsteroidal Anti-inflammatory Drug.
- Author:
Ji Hyun SONG
1
;
Ki Nam SHIM
;
Hyun Joo SONG
;
Hee Jung OH
;
Kum Hei RYU
;
Hye Jung YEOM
;
Seong Eun KIM
;
Tae Hun KIM
;
Hye Kyung JUNG
;
Sung Ae JUNG
;
Kwon YOO
;
Il Hwan MOON
Author Information
1. Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea. shimkn@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
NSAIDs;
Duodenal obstruction
- MeSH:
Anti-Inflammatory Agents, Non-Steroidal;
Appendectomy;
Duodenal Obstruction*;
Duodenal Ulcer;
Duodenum;
Follow-Up Studies;
Gastric Bypass;
Hemorrhage;
Humans;
Ketorolac;
Middle Aged;
Mortality;
Pain, Postoperative;
Peptic Ulcer;
Proton Pumps;
Pylorus
- From:Korean Journal of Gastrointestinal Endoscopy
2006;32(4):278-282
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Giant duodenal ulcer can be defined as a variant of peptic ulceration that exceeds 2 cm at the greatest diameter. The high mortality and morbidity of giant duodenal ulcer are directly related to the resultant perforation, obstruction and massive hemorrhage. The patient usually has a long history of an inadequately treated or neglected peptic ulcer, but this malady is rarely induced by nonsteroidal anti-inflammatory drugs (NSAIDs). A 60-year-old man was referred to us due to epigastric pain. He underwent appendectomy 1 week ago, and he was administered ketorolac (tarasyn(R)) for 5 days to control the postoperative pain. Esophagogastroduodenos copy (EGD) revealed a giant duodenal ulcer encircling the lumen from the pylorus to the postbulbar portion of the duodenum, and he was then treated with proton pump inhibitor. Two weeks later, the follow-up EGD showed complete duodenal obstruction at the bulb. He was treated by laparoscopic gastrojejunostomy. We report here on this case of duodenal obstruction that was induced by the short-term use of NSAIDs.