A Case of Enteropathy-Associated T-cell Lymphoma (EATL) Presenting Perforation after Chemotherapy for Primary Intestinal Lymphoma.
- Author:
Hyung Jun KIM
1
;
Sok Won HAN
;
Soon Min PARK
;
Chang Whan KIM
;
Sung Eun YANG
;
Hyeong Geun KIM
;
Keun Jong CHO
;
Tae Ho KIM
;
Sang Bum KANG
;
Young Seok CHO
;
Sung Soo KIM
;
Dong Soo LEE
;
Hiun Suk CHAE
;
Jea Na KIM
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. swhan54@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Enteropathy-associated T-cell lymphoma (EATL);
Hematochezia;
Perforation
- MeSH:
Adrenal Cortex Hormones;
Celiac Disease;
Colonoscopy;
Drug Therapy*;
Enteropathy-Associated T-Cell Lymphoma*;
Gastrointestinal Hemorrhage;
Humans;
Lymphoma*;
Lymphoma, T-Cell;
Male;
Middle Aged;
Mortality;
Prognosis;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
2006;32(4):287-292
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intestinal T-cell lymphomas are fairly uncommon, and can sometimes be associated with enteropathy. Enteropathy-associated T-cell lymphoma (EATL) is commonly accompanied by a nonspecific mucosal ulceration, similar to that observed as a complication of celiac disease. The clinical course of EATL is quite unfavorable, and tends to have a generally poor prognosis. When a tumor invades the bowel wall and is treated with corticosteroids and chemotherapy, cell lysis with perforation often occurs, particularly in case of lymphoma. Recent data indicate that extensive resection may improve local control, and eliminate the risk of early mortality due to visceral perforation or hemorrhaging in unresected lesions during chemotherapy. Here, we report the case of a 51-year-old male who was diagnosed with primary gastrointestinal lymphoma after colonoscopy, and presented with EATL after emergent exploratory laparatomy. We also include a review of the literature regarding this uncommon entity.
