A Case of Clostridium Septicum Sepsis Associated with Malignancy.
- Author:
Cheong Won PARK
1
;
Joon Young SONG
;
Cheol Hyun KIM
;
Jang Wook SOHN
;
Hee Jin CHEONG
;
Woo Joo KIM
;
Min Ja KIM
;
Seung Chul PARK
Author Information
1. Department of Ineternal Medicine, Korea University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Clostridium septicum sepsis;
Malignancy;
Diabetes mellitus
- MeSH:
Abdominal Pain;
Aged;
Anti-Bacterial Agents;
Clostridium septicum*;
Clostridium*;
Diabetes Mellitus;
Diarrhea;
Female;
Fever;
Humans;
Critical Care;
Lymphoma, T-Cell, Peripheral;
Nausea;
Neutropenia;
Sepsis*;
Vomiting
- From:Korean Journal of Infectious Diseases
2000;32(4):340-343
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clostridium septicum is a toxin producing anaerobic, motile, spore-forming, spindle shaped Gram positive rod that may cause devastating systemic illness in patients with neutropenia and underlying hematologic or gastrointestinal malignancy. Clostridium septicum sepsis usually have fulminating clinical courses, and unless the appropriate antibiotics are administered soon after admission, the outcome is fatal. We experienced a case of sepsis due to Clostridium septicum, in a 65-year-old woman with peripheral T-cell lymphoma and diabetes mellitus. She was admitted due to abdominal pain, fever, chilling, nausea, vomiting and watery diarrhea, followed by rapidly progressive course. This patient was not improved by intensive care and continuous antibiotic therapy, expired at the 4th hospital day. Clostridium septicum grew from premortem blood cultures.
