Induction of Anesthesia with Low-Dose Midazolam and Thiopental.
10.4097/kjae.1997.32.5.745
- Author:
Young Du NA
1
;
Young Ho JANG
;
Jung Kil CHUNG
Author Information
1. Department of Anesthesiology, Keimyung University, School of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Anesthetics;
intravenous;
midazolam;
thiopental
- MeSH:
Anesthesia*;
Anesthetics;
Arterial Pressure;
Blood Pressure;
Heart Rate;
Hemodynamics;
Humans;
Intubation;
Midazolam*;
Thiopental*
- From:Korean Journal of Anesthesiology
1997;32(5):745-749
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: This study was undertaken to evaluate the hemodynamic response of midazolam-thiopental coinduction technique compared with thiopental or midazolam induction after tracheal intubation. METHODS: 60 patients were divided into 3 groups. Group I thiopental 5 mg/kg induction groups: Group II, midazolam 0.2 mg/kg induction group: Group III 2 mg/kg of thiopental was injected intravenously to each patient 2min after 0.02 mg/kg of midazolam injected. After tracheal intubation, blood pressure and heart rate were measured for 5 minutes at 1 minute interval. Results: There were not significant differences in systolic, diastotic, mean arterial pressure and heart rate in 3 groups. CONCLUSIONS: Low dose midazolam-thiopental coinduction can be a useful method for induction because of same hemodynamic changes as to thiopental or midazolam alone.
