Chronic Kidney Disease and Associated Cardiovascular Risk Factors in Chinese with Type 2 Diabetes.
10.4093/dmj.2012.36.6.433
- Author:
Qing Lin LOU
1
;
Xiao Jun OUYANG
;
Liu Bao GU
;
Yong Zhen MO
;
Ronald MA
;
Jennifer NAN
;
Alice KONG
;
Wing Yee SO
;
Gary KO
;
Juliana CHAN
;
Chun Chung CHOW
;
Rong Wen BIAN
Author Information
1. Diabetes Care and Research Center, Jiangsu Province Institute of Geriatrics, Nanjing, China. bianrw@126.com
- Publication Type:Original Article
- Keywords:
Albuminuria;
Chronic kidney disease;
Diabetes mellitus, type 2;
Risk factors
- MeSH:
Albuminuria;
Anemia;
Asian Continental Ancestry Group;
China;
Cross-Sectional Studies;
Diabetes Mellitus, Type 2;
Glomerular Filtration Rate;
Humans;
Hypertension;
Kidney Diseases;
Odds Ratio;
Renal Insufficiency, Chronic;
Risk Factors
- From:Diabetes & Metabolism Journal
2012;36(6):433-442
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: To determine the frequency of chronic kidney disease (CKD) and its associated risk factors in Chinese type 2 diabetic patients, we conducted a cross-sectional study in Nanjing, China, in the period between January 2008 and December 2009. METHODS: Patients with type 2 diabetes under the care by Jiangsu Province Official Hospital, Nanjing, China were invited for assessment. CKD was defined as the presence of albuminuria or estimated glomerular filtration rate <60 mL/min/1.73 m2. Albuminuria was defined as urinary albumin-to-creatinine ratio > or =30 mg/g. RESULTS: We recruited 1,521 urban Chinese patients with type 2 diabetes (mean age, 63.9+/-12.0 years). The frequency of CKD and albuminuria was 31.0% and 28.9%, respectively. After adjusted by age and sex, hypertension, anemia and duration of diabetes were significantly associated with CKD with odds ratio (95% confidence interval) being 1.93 (1.28 to 2.93), 1.70 (1.09 to 2.64), and 1.03 (1.00 to 1.06), respectively. CONCLUSION: In conclusion, CKD was common in the urban Nanjing Chinese with type 2 diabetes. Strategies to prevent or delay progression of kidney disease in diabetes should be carried out at the early disease course of type 2 diabetes.
