A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease.
- Author:
Chun Chi LIN
1
;
Shu Chen WEI
;
Been Ren LIN
;
Wen Sy TSAI
;
Jinn Shiun CHEN
;
Tzu Chi HSU
;
Wei Chen LIN
;
Tien Yu HUANG
;
Te Hsin CHAO
;
Hung Hsin LIN
;
Jau Min WONG
;
Jen Kou LIN
Author Information
- Publication Type:Multicenter Study ; Original Article
- Keywords: Colitis, ulcerative; Surgery; Prognosis
- MeSH: Colectomy; Colitis, Ulcerative*; Cooperative Behavior; Diagnosis; Emergencies; Follow-Up Studies; Hemorrhage; Humans; Inflammatory Bowel Diseases*; Mortality; Prognosis; Retrospective Studies*; Sepsis; Taiwan*; Ulcer*
- From:Intestinal Research 2016;14(3):248-257
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: With the recent progress in medical treatment, surgery still plays a necessary and important role in treating ulcerative colitis (UC) patients. In this study, we analyzed the surgical results and outcomes of UC in Taiwan in the recent 20 years, via a multi-center study through the collaboration of Taiwan Society of IBD. METHODS: A retrospective analysis of surgery data of UC patients from January 1, 1995, through December 31, 2014, in 6 Taiwan major medical centers was conducted. The patients' demographic data, indications for surgery, and outcome details were recorded and analyzed. RESULTS: The data of 87 UC patients who received surgical treatment were recorded. The median post-operative follow-up duration was 51.1 months and ranged from 0.4 to 300 months. The mean age at UC diagnosis was 45.3±16.0 years and that at operation was 48.5±15.2 years. The 3 leading indications for surgical intervention were uncontrolled bleeding (16.1%), perforation (13.8%), and intractability (12.6%). In total, 27.6% of surgeries were performed in an emergency setting. Total or subtotal colectomy with rectal preservation (41.4%) was the most common operation. There were 6 mortalities, all due to sepsis. Emergency operation and low pre-operative albumin level were significantly associated with poor survival (P=0.013 and 0.034, respectively). CONCLUSIONS: In the past 20 years, there was no significant change in the indications for surgery in UC patients. Emergency surgeries and low pre-operative albumin level were associated with poor survival. Therefore, an optimal timing of elective surgery for people with poorly controlled UC is paramount.
