Change in the diagnosis of inflammatory bowel disease: a hospital-based cohort study from Korea.
- Author:
Ho Su LEE
1
;
Jaewon CHOE
;
Hyo Jeong LEE
;
Sung Wook HWANG
;
Sang Hyoung PARK
;
Dong Hoon YANG
;
Kyung Jo KIM
;
Byong Duk YE
;
Jeong Sik BYEON
;
Seung Jae MYUNG
;
Yong Sik YOON
;
Chang Sik YU
;
Jin Ho KIM
;
Suk Kyun YANG
Author Information
- Publication Type:Original Article
- Keywords: Crohn disease; Ulcerative colitis; Diagnosis; Inflammatory bowel diseases
- MeSH: Chungcheongnam-do; Cohort Studies*; Colitis; Colitis, Ulcerative; Crohn Disease; Diagnosis*; Follow-Up Studies; Humans; Inflammatory Bowel Diseases*; Korea*; Referral and Consultation
- From:Intestinal Research 2016;14(3):258-263
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Accurately diagnosing inflammatory bowel disease (IBD) remains a challenge, but is crucial for providing proper management for affected patients. The aim of the present study was to evaluate the frequency of change in diagnosis in Korean patients who were referred to our institution with a diagnosis of IBD. METHODS: We enrolled 1,444 patients diagnosed with ulcerative colitis (UC) and 1,452 diagnosed with Crohn's disease (CD), who had been referred to the Asan Medical Center between January 2010 and December 2014. These patients were assessed and subsequently classified as having UC, CD, indeterminate colitis, possible IBD, or non-IBD. RESULTS: During a median follow-up of 15.9 months, 400 of the 2,896 patients (13.8%) analyzed in this study experienced a change in diagnosis. A change in diagnosis from UC to CD, or vice-versa, was made in 24 of 1,444 patients (1.7%) and 23 of 1,452 patients (1.6%), respectively. A change to a non-IBD diagnosis was the most common modification; 7.5% (108 of 1444) and 12.7% (184 of 1452) of the patients with a referral diagnosis of UC and CD, respectively, were reclassified as having non-IBD. Among the 292 patients who were ultimately determined not to have IBD, 135 (55 UC and 80 CD cases) had received IBD-related medication. CONCLUSIONS: There are diagnostic uncertainties and difficulties in relation to IBD. Therefore, precise assessment and systematic follow-up are essential in the management of this condition.
