A New Sesterterpene from the Korean Sarcotragus sp. Sponge.
10.20307/nps.2015.21.4.237
- Author:
Jung Kyun WOO
1
;
Ju Eun JEON
;
Bora KIM
;
Chung J SIM
;
Dong Chan OH
;
Ki Bong OH
;
Jongheon SHIN
Author Information
1. Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742, Korea. shinj@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Sponge;
Sarcotragus sp.;
Sarcotragin C;
Norsesterterpene;
Cytotoxicity
- MeSH:
Korea;
Porifera*
- From:Natural Product Sciences
2015;21(4):237-239
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sarcotragin C (1), a new sesterterpene metabolite was isolated from a Sarcotragus sp. sponge collected from Chuja Island, Korea. On the basis of the combined spectroscopic analyses, the structure of this compound was determined to be a linear norsesterterpene containing a leucine-derived gamma-lactam moiety. This compound exhibited moderate cytotoxicity against K562 and A549 cell-lines.
