Significance of an Early Clinical Course during the External Ventricular Drainage in Thalamic Hemorrhage.
- Author:
Ra Sun KIM
1
;
Hack Gun BAE
;
Seok Mann YOON
;
Jae Won DOH
;
Kyeong Seok LEE
;
Il Gyu YUN
Author Information
1. Department of Neurosurgery, Soonchunhyang University Chonan Hospital, Cheonan, Korea. hgbaeb@schch.co.kr
- Publication Type:Original Article
- Keywords:
Thalamic hemorrhage;
External ventricular drainage;
Hematoma enlargement;
Shunt
- MeSH:
Coma;
Drainage*;
Hematoma;
Hemorrhage*;
Humans;
Mortality
- From:Journal of Korean Neurosurgical Society
2004;35(1):81-87
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The purpose of this study is to investigate the significance of an early clinical course during the external ventricular drainage(EVD) in patients with thal amic hemorrhage. METHODS: During the last 11 years(1990-2000), a hundred patients with thalamic hemorrhage who underwent EVD were studied. Thirty-four patients underwent temporary closing of EVD at the mean interval of 4.5 days after EVD. The clinical course was divided into 3 groups according to change of Glasgow Coma Scale(GCS) scores of 2 or more within 3 days after EVD compared with those just before EVD: deteriorated, unchanged, and improved. RESULTS: The factors affecting mortality were unchanged(odds ratio [OR] 0.05, 95% confidence interval [CI]0.01-0.38, p=0.0028) and deteriorated clinical course(OR 0.06, 95% CI 0.01-0.38, p=0.0033), GCS scores at the time of admission(OR 1.3, 95% CI 1.02-1.66, p=0.0346), amount of hematoma(OR 0.91, 95% CI 0.83-1.00, p=0.0461) and hematoma enlargement(OR 0.06, 95% CI 0.01-0.65, p=0.0198). The factor affecting the early clinical deterioration was the hematoma enlargement(OR 0.11, 95% CI 0.03-0.38, p=0.0005). The shunt operation was predicted in patients who showed the clinical improvement after EVD followed by the clinical deterioration within 48 hours after temporary closing of EVD. CONCLUSION: It is suggested that an early clinical course during the maintenance of EVD is important to predict mortality and necessity of shunt operation.
