Clinical Characteristics of Female Epilepsy Patients with Cyclic Exacerbation Related to Menstruation.
- Author:
Oh Young BANG
1
;
Yong Tae KWAK
;
Soo Chul PARK
;
Byung In LEE
Author Information
1. Department of Neurology, College of Medicine, Yonsei University, Korea.
- Publication Type:Original Article
- MeSH:
Anticonvulsants;
Epilepsy*;
Female*;
Humans;
Menstrual Cycle;
Menstruation*;
Neurologic Manifestations;
Seizures
- From:Journal of the Korean Neurological Association
1995;13(3):551-558
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The relationship of seizure and menstruation was investigated in me hundred thirty six female epileptic patients attending regularly to the Yonsei Epilepsy Clinic. Cyclic preponderance was accepted when more than 50% of total number of seizure occurred in one menstrual phase. Cyclic exacerbatim of seizur% during menstrual cycle occurred in 35%(48) of patients with 65% of them(23% of total patients) occuring during perimenstrual phase, consistent with catamenial epilepsy, 19% during midcyclic phase, and 8% each in early and late phase, respectively. Patients with focal neurologic deficit (p value <0. 05), perimenstrual tensim (p value <0.001), frequent seizure attack (p value <0.05), past history of delayed development (p value <0.05), electroencephalographic evidence of focal slowing (p value <0.01) had more cyclic exacerbation of seizure during perimenstrual, period. These patients also had poor response to anticonvulsants. These factors related with the cyclic exacerbation of seizure frequency should be considered for clinical approach to female epileptic patients.
