Clinical Syndrome of Corticobasal Degeneration.
- Author:
Sang Bock LEE
1
;
Myung Sik LEE
;
Joo Hyuk IM
;
Joon Shik MOON
;
Jae Hyeon PARK
;
Myung Chong LEE
Author Information
1. Department of Neurology, Yongdong Severance Hospital, Yonsei University College of Medicine, Korea.
- Publication Type:Original Article
- MeSH:
Apraxias;
Basal Ganglia;
Brain;
Cerebellar Ataxia;
Diagnosis;
Dystonia;
Emigrants and Immigrants;
Extremities;
Humans;
Magnetic Resonance Imaging;
Paralysis;
Supranuclear Palsy, Progressive
- From:Journal of the Korean Neurological Association
1995;13(3):565-573
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clinical features of corticobasal degeneration (CBD) can be characterized by an asymmetric akinetic-rigid syndrome with variable combinations of other deficits (corticospinal tract signs, supranuclear gaze palsy, cerebellar ataxia, cortical sensory loss, alien limb behavior, dystonia and myoclonus). Such unique combination of clinical features of CBD have lead to the general agreement that clinical diagnosis of CBD is reliable. We describe 6 patients presenting with clinical features compatible with CBD. Three had characteristic clinical features of CBD; one showed clinical features compatible with progressive supranuclear palsy, but also had apraxia and cortical sensory disturbances; one had an early CBD. The remaining one had clinical features compatible with CBD, but brain magnetic resonance imaging study showed multiple small lesions involving periventricular white matter and basal ganglia bilaterally.
