Porencephaly: An Autopsy Case Report.
- Author:
In Sook KIM
;
Jin Hee SHON
;
Hyo Sook PARK
;
Je Geun CHI
- Publication Type:Case Report
- MeSH:
Infant;
Male;
Female;
Infant, Newborn;
Humans
- From:Korean Journal of Pathology
1988;22(2):199-203
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Porencephaly is a rare congenital anomaly characterized by a cavitary hole extending from the cerebral mantle to the ventricle of the brain and covered by leptomeningeal membrane. It is now generally believed that the porencephaly represents a fetal or neonatal destructive process of the neural tissue. Authors experienced an autopsy case of bilateral porencephaly in a 35-day-old Korean male infant who died of sepsis. The brain weighed 150 gms and morphologically well formed except for two large symmetric defects at the fronto-parietal region. These defects were characterized by cleft-like shape, covering the entire cerebral mantle with resultant direct communication between ventricular cavity and leptomeninges. Thin leptomeningeal trabeculae were covering the cavity. There was a smooth transition between ependyma and roof of the defects. There are focal, microscopic cerebral infarct and abscess without connection with the cavitary lesion. The remaining central nervous system was unremarkable.
