A Study on Epidermal Cytoplasmic Antibodies in Patients with Various Malignancies.
- Author:
Sang Lip CHUNG
;
Moo Gyu SUH
- Publication Type:Original Article
- Keywords:
Epidermal cytoplasmic antibody;
Malignancy
- MeSH:
Antibodies*;
Cytoplasm*;
Fluorescent Antibody Technique, Indirect;
Hodgkin Disease;
Humans;
Immunoglobulin A;
Immunoglobulin G;
Incidence;
Lung Neoplasms;
Rectal Neoplasms;
Stomach Neoplasms
- From:Korean Journal of Dermatology
1985;23(6):719-725
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
For the purpose of studying the compiarson of normal persons with patients with malignant tumors, the author investigated the incidence of epidermal cytoplasmic antibodies (EC-Ab) with sera taken from 15 normal persons, 38 patients with malignant tumors, and 2 patients with miscellaneous disorders by method of indirect immunofluorescence. The results were as follow: 1) .Positive reactions of EC-Ab were found in 2(13%) of 15 normal persons and 9 (24%) of 38 patients with malignant tumors. 2)Incidence of positive reactions of EC-Ab in various types of malignant turnors were found in 3(75%) of 4 patients with lung cancer, 2(40%) of 5 patients with rectal cancer, 3(13%) of 24 patients with stomach cancer, and 1(100%) patient with Hodgkins lymphoma. 3) Among 9 patients with malignant tumors of positive EC-Ab, 5 patients yielded the upper epiderrnaI cytoplasrnic (UEC) antibodies, 3 patients the general epidermal cytoplasmic (GEC) antibodies, and 1 patient basal cell layer (BCL) antibody. 4) A.mong 9 patients with malignant tumors of positive, the deposition of IgG was discovered in 7 patients, IgA in 1 patient and C, in 1 patient.
