Investigation of Cell Mediated Immunity in Patients with Behcet's Syndrome, Using the DNCB Sensitization.
- Author:
Dong Sik BANG
;
Sung Nack LEE
;
Duck Hyun KIM
;
In Whan NAM
- Publication Type:Original Article
- Keywords:
Behcet's syndrome;
DNCB sensitization
- MeSH:
Behcet Syndrome*;
Dinitrochlorobenzene*;
Humans;
Immunity, Cellular*;
Lymphocyte Activation;
T-Lymphocyte Subsets;
T-Lymphocytes;
T-Lymphocytes, Helper-Inducer
- From:Korean Journal of Dermatology
1985;23(6):769-773
- CountryRepublic of Korea
- Language:English
-
Abstract:
Various immunologic investigations of 159 patients with Behqets syndrome undertaken included; the DNCB sensitization test, total T-cells and T-cell subsets and the lymphocyte transformation test using PHA. The percentage of positive esponsiveness to DNCB decreased in the order of possible (65%), suspected (60%), incomplete (37%) and complete type (37%), The number of patients with impaired LTT was larger in the group of patients with DNCB( + ) responsiveness (seventeen of 32) than in DNCB(+) group (six of 25), There was significant impairment of cell mediated immunity in Behcets syndrome compared to normal subjects, when analyzed by the impaired LTT and decreased proportions of helper T-cells.
