A Case of Chorea Associated with Antipholipid Antibodies in Patients with Systemic Lupus Erythematosus.
- Author:
Young Suk CHO
1
;
Bum Soon CHOI
;
Kyung Ah YOH
;
Hyung In YANG
;
Sung Hwan PARK
;
Sang Heon LEE
;
Chul Soo CHO
;
Ho Youn KIM
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Chorea;
Antiphosphplipid antibodies
- MeSH:
Adolescent;
Antibodies*;
Antibodies, Anticardiolipin;
Antibodies, Antiphospholipid;
Antiphospholipid Syndrome;
Ataxia;
Chorea*;
Female;
Haloperidol;
Humans;
Ischemia;
Lupus Erythematosus, Systemic*;
Movement Disorders;
Subthalamic Nucleus;
Thrombocytopenia;
Warfarin
- From:The Journal of the Korean Rheumatism Association
1995;2(2):207-211
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The neuropsychiatric manifestations of systemic lupus erythematosus (SLE) are diverse but, among them, movement disorders such as chorea, ataxia are uncommon. We describe a 16 year old female SLE patient with positive anticardiolipin antibody who developed sudden onset of chorea. The clinical and laboratory findings that positive anticardiolipin antibody, thrombocytopenia, chorea were suggested antiphospholipid syndrome. Although the pathophysiology of chorea in SLE is unknown, an association with. antiphospholipid antibodies has been suggested. The underlying pathogenic mechanism of this case could not established but was most likely to have been an ischemia of the contralateral subthalamic nucleus. She was treated with corticosteroid, haloperidol and warfarin and now chorea is disappered.
