MR Findings of Congenital Craniocerebral Anomaly: Correlation with Seizures and Developmental Delay.
10.3348/jkrs.1995.33.1.7
- Author:
Heoung Keun KANG
;
Jeong Jin SEO
;
Hyon De CHUNG
;
Yun Hyeon KIM
;
Seog Wan KO
;
Jong Hun YOON
;
Hyun Ju KIRN
;
Hyeong Kil KIM
- Publication Type:Original Article
- MeSH:
Humans;
Lissencephaly;
Magnetic Resonance Imaging;
Malformations of Cortical Development;
Neurocutaneous Syndromes;
Neurologic Manifestations;
Neuronal Migration Disorders;
Neurons;
Parietal Lobe;
Rabeprazole;
Retrospective Studies;
Seizures*;
Tuberous Sclerosis
- From:Journal of the Korean Radiological Society
1995;33(1):7-14
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate characteristic MR findings of craniocerebral anomaly and its relationship with neurologic manifestations. MATERIALS AND METHODS: We retrospectively reviewed MR images of 36 patients with craniocerebral anomaly diagnosed by MRI and clinical courses. We correlated the characteristic MR findings in 41 lesions with neurologic manifestastions focusing on seizures and developmental delay. RESULTS: Twenty-three patients with seizures consisted of 14 patients(60%) with neuronal migration disorders and seven(30%) with phakomatosis, among which 18 patients(78%) had generalized type of seizures. Locations of the lesions were the parietal lobes in 11 patients(52%) and the subependymal or periventricular regions in seven(33%). Two patients with tuberous sclerosis had the lesions in both parietal and subependymal areas. Nine patients had the signs of developmental delay that were seen in the four(44%) with schizencephaly, two (22%) with tuberous sclerosis, two(22%) with heterotopia, and one(ll %) with pachygyria. CONCLUSION: Neuronal migration anomaly was relatively common lesion that presented neurologic manifestations such as seizures and developmental delay. Generalized type of seizures was common. We were able to diagnose these anomalies using the MRI that helped establish therapeutic plans.
