Endobronchial Brachytherapy for MalignantAirway Obstruction: Low Dose Rate Versus High Dose Rate.
- Author:
Young Kap CHO
1
Author Information
1. Department of Radiation Oncology, Inha University Hospital, Inchon, Korea.
- Publication Type:Original Article
- Keywords:
Endobronchial Brachytherapy;
Low Dose Rate;
High Dose Rate;
RadiationTherapy;
Palliation;
Malignant Airway Obstruction
- MeSH:
Airway Obstruction;
Brachytherapy*;
Bronchoscopy;
Follow-Up Studies;
Humans;
Lung;
Radius;
Retrospective Studies;
Survival Rate;
Thorax;
Tomography, X-Ray Computed
- From:Journal of the Korean Society for Therapeutic Radiology
1996;14(2):123-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This is a retrospective study to compare the palliation rates, survival rates and complications of low dose rate and high dose rate endobronchial brachytherapy in the management of malignant airway obstruction. METHODS AND MATERIALS: Forty three consecutive patients with malignant airway compromise from primary or metastatic lung tumors were treated with low dose rate(LDR) endobronchial Iridium-192 insertion (21 patients) between October 1988 and June 1992, and high dose rate(HDR) endobronchial brachytherapy(22 patients) between August 1992 and April 1994 with palliative aim. Flexible fiberoptic bronchoscopy under fluoroscopic control was utilized in all 91 provedures. Twenty seven LDR provedures delivereda dose of 5-7.5 Gy to a 1.0 cm radius respectively. RESULTS: Subjective and objective responses to treatments were evaluated on follow-up examinations by clinical examination, chest x-rays and CT scan of the chest had been demonstrated on 8 LDR patients and 10 HDR patients. CONCLUSION: The technique of LDR and HDR endobronchial brachytherapy is simple and well tolerated procedure with minimal morbidity. It provides excellent palliation by keeping airway patent in these short life-spanned patients.
