Primary Intracranial Squamous Cell Carcinoma in the Brain Stem with a Cerebellopontine Angle Epidermoid Cyst.
10.3340/jkns.2008.44.6.401
- Author:
Min Su KIM
1
;
Oh Lyong KIM
Author Information
1. Department of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea. olkim@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Squamous cell carcinoma;
Epidermoid cyst;
Brain stem;
Cerebellopontine angle
- MeSH:
Aged;
Brain;
Brain Stem;
Carcinoma, Squamous Cell;
Cerebellopontine Angle;
Deglutition;
Epidermal Cyst;
Female;
Humans;
Hypesthesia;
Magnetic Resonance Imaging;
Paresis;
Positron-Emission Tomography;
Recurrence
- From:Journal of Korean Neurosurgical Society
2008;44(6):401-404
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from a preexisting benign epidermoid cyst. We report a rare case of primary intracranial squamous cell carcinoma in the brain stem with a cerebellopontine angle (CPA) epidermoid cyst. A 72-year-old female suffered from progressive left hemiparesis, difficulty in swallowing, and right hemifacial numbness. Diffusion-weighted magnetic resonance imaging revealed a high signal intensity (SI) lesion in the CPA region and an intra-axially ring-enhanced cystic mass in the right brain stem with low SI. Whole-body positron emission tomography showed no evidence of metastatic disease. The histological findings revealed a typical epidermoid cyst in the CPA region and a squamous cell carcinoma in the brain stem. We speculate that the squamous cell carcinoma may have been developed due to a chronic inflammatory response by the adjacent epidermoid cyst. The patient underwent a surgical resection and radiotherapy. After 12 months, she had no evidence of recurrence.
