Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia.
- Author:
Haruki ASANO
1
;
Toshihiko TOMITA
;
Kumiko NAKAMURA
;
Takahisa YAMASAKI
;
Takuya OKUGAWA
;
Takashi KONDO
;
Tomoaki KONO
;
Katsuyuki TOZAWA
;
Yoshio OHDA
;
Tadayuki OSHIMA
;
Hirokazu FUKUI
;
Kazuhito FUKUSHIMA
;
Shozo HIROTA
;
Jiro WATARI
;
Hiroto MIWA
Author Information
- Publication Type:Original Article
- Keywords: Dyspepsia; Motility; Prevalence; Stomach
- MeSH: Asian Continental Ancestry Group; Dyspepsia*; Healthy Volunteers; Humans; Meals; Prevalence*; Radionuclide Imaging; Stomach; Volunteers; Weights and Measures
- From:Journal of Neurogastroenterology and Motility 2017;23(3):392-399
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of this study are to (1) investigate the prevalence of gastric motility disorders and (2) evaluate the association between gastric motility abnormalities and dyspeptic symptoms using gastric scintigraphy in the PDS type of FD. METHODS: Forty healthy subjects and 94 PDS type FD patients were enrolled in the study. The volunteers and patients ingested a radiolabeled (technetium-99m) solid test meal, and scintigraphic images were recorded. Gastric accommodation and emptying were assessed by scintigraphic imaging. The patients’ dyspeptic symptoms were also explored using self-completed symptom questionnaires with 10 variables (4 scales, 0–3 points) at the same time. RESULTS: In 94 Japanese FD patients, the prevalence of impaired gastric accommodation and delayed emptying were 14.9% (14/94) and 10.6% (10/94), respectively. Gastric motility abnormalities were seen in 25.5% (24/94) of FD patients. There was no association between gastric motility abnormalities and dyspeptic symptoms. CONCLUSIONS: Gastric motility abnormalities were seen in 25.5% of Japanese PDS type FD patients. However, there was no association between gastric motility abnormalities and dyspeptic symptoms on gastric scintigraphy.
