Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus: A Case Report.

Author: Hyun Min BAE ¹ ; Yoo Jung PARK ; Young Hoon KIM ; Dong Eon MOON
Author Information

1. Department of Anesthesiology and Pain Medicine, Catholic Medical Center, School of Medicine, The Catholic University of Korea, Seoul, Korea. demoon@catholic.ac.kr
Publication Type:Case Report
Keywords: carbamazepine; drug hypersensitivity reaction; Stevens-Johnson syndrome; trigerminal neuralgia
MeSH: Carbamazepine; Humans; Pruritus; Skin; Stevens-Johnson Syndrome; Trigeminal Neuralgia
From:The Korean Journal of Pain 2013;26(1):80-83
CountryRepublic of Korea
Language:English
Abstract: Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommend gradual titration when initiating treatment with carbamazepine.