Effectiveness of Oral Glycopyrrolate Use in Compensatory Hyperhidrosis Patients.
- Author:
Tai Kyung GONG
1
;
Do Wan KIM
Author Information
- Publication Type:Brief Communication
- Keywords: anticholinergic agents; compensatory hyperhidrosis; glycopyrrolate; sympathectomy
- MeSH: Anxiety; Anxiety Disorders; Autonomic Nervous System; Cholinergic Antagonists; Depression; Glycopyrrolate; Humans; Hyperhidrosis; Quality of Life; Reflex; Sweat; Sweating; Sympathectomy
- From:The Korean Journal of Pain 2013;26(1):89-93
- CountryRepublic of Korea
- Language:English
- Abstract: Compensatory hyperhidrosis or reflex hyperhidrosis is the increase in sweating in the postoperative stage of thoracic sympathectomy or lumbar sympathectomy. It shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oralglycopyrrolate is one of the treatment options available. This study reviewed case notes in a series of 19 patients with compensatory hyperhidrosis. We made a comparison between the Milanez de Campos score of a pre-glycopyrrolate medication group and the Milanez de Campos score of a post-glycopyrrolate medication group. The Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the pre-medication and post-medication groups. In the post-glycopyrrolate medication group, there was decrease in the Milanez de Campos score, BAI score, and BDI score (P < 0.05). But no meaningful change was seen in the ANS score in the post-glycopyrrolate medication group (P > 0.05). Glycopyrrolate is an effective medication in the treatment of compensatory hyperhidrosis that, can alleviate anxiety and improve patients' quality of life.
