Clinical Characteristics and Treatment Strategies in Female Patients with Obsessive-Compulsive Disorder.
- Author:
Hyun Ju HONG
1
;
Chan Hyung KIM
Author Information
1. Department of Neuropsychiatry, Hallym University College of Medicine, Anyang, Korea.
- Publication Type:Review
- Keywords:
Female;
Obsessive-compulsive disorder;
Clinical characteristics;
Treatment response
- MeSH:
Age of Onset;
Comorbidity;
Female*;
Genetic Predisposition to Disease;
Humans;
Life Change Events;
Male;
Menarche;
Obsessive-Compulsive Disorder*;
Population Characteristics;
Postpartum Period
- From:Journal of Korean Neuropsychiatric Association
2006;45(2):93-99
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This article reviews clinical characteristics, neurobiological aspects and treatment strategies in female patient with obsessive-compulsive disorder (OCD) compared to male. Female with OCD had a later age of onset and different patterns of OCD symptomatology and comorbidity. Female with OCD showed more favorable course and also reported more frequently stressful event in preceding OCD onset. The onset or worsening of OCD was related to female reproductive cycle events, especially at menarche and postpartum. There is a paucity of investigation regarding gender difference in treatment response in OCD. It has been suggested that gender may contribute to the clinical and biological heterogeneity of OCD and also sexually dimorphic pattern of genetic susceptibility to OCD may be present.
