A Case of Adrenocortical Carcinoma Secreting Cortisol and Aldosterone.
10.12701/yujm.2012.29.2.132
- Author:
Jiyoon HA
1
;
Min Kyung KIM
;
Yoon Jin CHA
;
Seung Kyu KIM
;
Gi Young YUN
;
Kwangwon RHEE
;
Joon Seong PARK
;
Eun Suk CHO
;
Chul Woo AHN
;
Jong Suk PARK
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. pjs00@yuhs.ac
- Publication Type:Case Report
- Keywords:
Adrenocortical carcinoma;
Aldosterone;
Cortisol;
Cushing's syndrome;
Primary aldosteronism
- MeSH:
Adrenalectomy;
Adrenocortical Carcinoma;
Aldosterone;
Cushing Syndrome;
Dexamethasone;
Female;
Humans;
Hydrocortisone;
Hypertension;
Hypokalemia;
Virilism;
Weight Gain
- From:Yeungnam University Journal of Medicine
2012;29(2):132-135
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Adrenocortical carcinomas are rare and frequently aggressive tumors that may be functional (hormone-secreting) and may cause Cushing's syndrome or virilization, or non-functional and manifest as an abdominal mass. This paper reports the case of a 77-year-old woman with cortisol- and aldosterone-secreting adrenal carcinoma. The patient complained of general weakness, a moon face, and weight gain. She also had hypokalemia and hypertension. Her endocrinological data showed excessive aldosterone production and non-suppressible cortisol production in a low-dose dexamethasone suppresion test. Her abdominal CT showed a right adrenal mass. She underwent right adrenalectomy, and her histology revealed the presence of adrenocortical carcinoma. After adrenalectomy, her hypokalemia returned to normal and she is being treated with hydrocortisone.