A Case of Recurrent Exercise-Induced Acute Renal Failure and Renal Hypouricemia with R90H Mutation in a SCL22A12 Gene.
10.12701/yujm.2012.29.2.150
- Author:
Ae Jin KIM
1
;
Soo Yong PARK
;
Ji Yong JUNG
;
Jae Hyun CHANG
;
Hyun Hee LEE
;
Wook Yung CHUNG
;
Han RO
Author Information
1. Department of Internal Medicine, Gachon Unniversity Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea. godad@gilhospital.com
- Publication Type:Case Report
- Keywords:
Acute kidney injury;
Renal hypouricemia;
Genetic analysis
- MeSH:
Acute Kidney Injury;
Genetic Counseling;
Humans;
Ischemia;
Recurrence;
Renal Tubular Transport, Inborn Errors;
Urinary Calculi
- From:Yeungnam University Journal of Medicine
2012;29(2):150-152
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute renal failure with severe loin pain and patch renal ischemia after anaerobic exercise (ALPE) is a rare cause of exercise-induced acute kidney injury. Some ALPE patients also have renal hypouricemia. Mutations in the SCL22A12 gene are among the major factors of hypouricemia. Education for the prevention of relapse and genetic counseling should be recommended to ALPE patients with renal hypouricemia. This paper reports a 25-year-old man who showed recurrent exercise-induced ARF and renal hypouricemia with R90H mutation in his SCL22A12 gene.
