Treatment of Atopic Dermatitis: an Update and Review of the Literature.
- Author:
Tae Yoon KIM
1
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. tykimder@catholic.ac.kr
- Publication Type:Review
- Keywords:
Atopic dermatitis;
Biologics;
Calcineurin inhibitors;
Immunomodulatory drugs
- MeSH:
Antibodies, Anti-Idiotypic;
Biological Agents;
Calcineurin;
Dermatitis, Atopic;
Oligodeoxyribonucleotides;
Skin Diseases
- From:Pediatric Allergy and Respiratory Disease
2009;19(3):209-219
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Atopic dermatitis is a chronic, relapsing, inflammatory skin disease, with genetic and environmental backgrounds. Successful management of atopic dermatitis requires a multipronged approach. Management should compromise of a disease-adapted treatment which combines adjuvant basic therapy, symptomatic relief and, if needed, anti-inflammatory treatment and the identification and avoidance of trigger factors. Topical calcineurin inhibitors are also considered to be good alternatives for the long-term control of severe atopic dermatitis. Also, new therapies such as immunomodulatory drugs, biologics, anti-IgE therapy, and CpG oligodeoxynucleotides (ODN) are considered to be effective in treatment of atopic dermatitis.