Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey.
10.4093/dmj.2014.38.6.480
- Author:
Jung Min KIM
1
;
Jae Won HONG
;
Jong Chul WON
;
Jung Hyun NOH
;
Kyung Soo KO
;
Byoung Doo RHEE
;
Dong Jun KIM
Author Information
1. Department of Internal Medicine, Cardiovascular and Metabolic Disease Center, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
- Publication Type:Brief Communication
- Keywords:
Diabetes mellitus;
Diagnosis;
Hemoglobin A, glycated
- MeSH:
Adult;
Blood Glucose*;
Diabetes Mellitus;
Diagnosis;
Fasting*;
Hemoglobin A, Glycosylated*;
Humans;
Korea;
Nutrition Surveys*;
ROC Curve;
Sensitivity and Specificity
- From:Diabetes & Metabolism Journal
2014;38(6):480-483
- CountryRepublic of Korea
- Language:English
-
Abstract:
We aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years of age were included in the analysis. A point-wise area under the receiver operating characteristic curve was used to estimate the optimal A1c cutoff value. A1c threshold of 6.1% produced the highest sum of sensitivity (85.2%) and specificity (90.5%) for FPG of 126 mg/dL (area under the curve, 0.941, P<0.001). A1c of 6.5% produced a sensitivity of 67.7% and specificity of 98.0% for FPG of 126 mg/dL. Considering A1c as one of three criteria for the diagnosis of diabetes and the specificity of an A1c cutoff of 6.5%, the current diagnostic criteria of A1c> or =6.5% might be acceptable in the Korean adult population.
