Radiofrequency ablation of very-early-stage hepatocellular carcinoma inconspicuous on fusion imaging with B-mode US: value of fusion imaging with contrast-enhanced US.
- Author:
Ji Hye MIN
1
;
Hyo Keun LIM
;
Sanghyeok LIM
;
Tae Wook KANG
;
Kyoung Doo SONG
;
Seo youn CHOI
;
Hyunchul RHIM
;
Min Woo LEE
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: Hepatocellular carcinoma; Radiofrequency ablation; Contrast-enhanced ultrasonography; Sonazoid; Fusion imaging
- MeSH: Adult; Aged; Carcinoma, Hepatocellular/*diagnosis/radiography/ultrasonography; Catheter Ablation; Contrast Media/diagnostic use; Female; Ferric Compounds/diagnostic use; Humans; Iron/diagnostic use; Liver Neoplasms/*diagnosis/radiography/ultrasonography; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Oxides/diagnostic use; Retrospective Studies; Tomography, X-Ray Computed
- From:Clinical and Molecular Hepatology 2014;20(1):61-70
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: To determine the value of fusion imaging with contrast-enhanced ultrasonography (CEUS) and computed tomography (CT)/magnetic resonance (MR) images for percutaneous radiofrequency ablation (RFA) of very-early-stage hepatocellular carcinomas (HCCs) that are inconspicuous on fusion imaging with B-mode ultrasound (US) and CT/MR images. METHODS: This retrospective study was approved by our institutional review board and the requirement for informed consent was waived. Fusion imaging with CEUS using Sonazoid contrast agent and CT/MR imaging was performed on HCCs (<2 cm) that were inconspicuous on fusion imaging with B-mode US. We evaluated the number of cases that became conspicuous on fusion imaging with CEUS. Percutaneous RFA was performed under the guidance of fusion imaging with CEUS. Technical success and major complication rates were assessed. RESULTS: In total, 30 patients with 30 HCCs (mean, 1.2 cm; range, 0.6-1.7 cm) were included, among which 25 (83.3%) became conspicuous on fusion imaging with CEUS at the time of the planning US and/or RFA procedure. Of those 25 HCCs, RFA was considered feasible for 23 (92.0%), which were thus treated. The technical success and major complication rates were 91.3% (21/23) and 4.3% (1/23), respectively. CONCLUSIONS: Fusion imaging with CEUS and CT/MR imaging is highly effective for percutaneous RFA of very-early-stage HCCs inconspicuous on fusion imaging with B-mode US and CT/MR imaging.
