A case of vancomycin-induced drug hypersensitivity syndrome.
10.3345/kjp.2008.51.11.1228
- Author:
Kyung Sun MIN
1
;
Woo Yeon CHOI
;
Eun Song SONG
;
Dong Kyun HAN
;
Young Kuk CHO
;
Jae Sook MA
Author Information
1. Department of Pediatrics, Chonnam National University Medical School, Gwang-Ju, Korea. cardiol@jnu.ac.kr
- Publication Type:Case Report
- Keywords:
Drug hypersensitivity syndrome;
Vancomycin
- MeSH:
Acute Kidney Injury;
Adrenal Cortex Hormones;
Child;
Drug Hypersensitivity;
Endocarditis;
Exanthema;
Fever;
Hepatitis;
Humans;
Hypersensitivity;
Vancomycin
- From:Korean Journal of Pediatrics
2008;51(11):1228-1231
- CountryRepublic of Korea
- Language:English
-
Abstract:
Drug hypersensitivity syndrome (DHS) has rarely been reported in association with vancomycin treatment. Here, we describe an 11-year-old girl who developed fever and a maculopapular rash on day 18 of intravenous vancomycin for treatment of infective endocarditis. The patient presented with fever, a maculopapular skin rash, hepatitis, and acute renal failure caused by vancomycin-induced DHS. The symptoms resolved in less than 24 h after withdrawal of vancomycin and treatment with corticosteroids. We present this case of DHS associated with vancomycin.
