Two Cases of Dermatofibroma with Sclerotic Fibroma-like Change.
- Author:
Yoonjin CHOI
1
;
Boncheol GOO
;
Jin Young JUNG
;
Hye Jin CHUNG
;
Kee Yang CHUNG
Author Information
1. Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. kychung@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Dermatofibroma;
Sclerotic fibroma
- MeSH:
Biopsy;
Collagen;
Eosinophils;
Fibroma;
Histiocytoma, Benign Fibrous*;
Humans;
Hyalin;
Skin
- From:Korean Journal of Dermatology
2007;45(6):581-584
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sclerotic fibroma is often regarded as a unique proliferating lesion, but some authors regard it as an end stage of other neoplasms, especially dermatofibroma. We report two cases of dermatofibroma with sclerotic fibroma-like change. The skin biopsy specimens from different patients showed a common finding of dermatofibroma, while some portions of the tumor were replaced by thick, hyalinized, eosinophilic collagen bundles and empty clefts with low cellularity, which was histologically similar to sclerotic fibroma. According to these findings, dermatofibroma with sclerotic fibroma-like change can be evidence of the possible pathogenesis of sclerotic fibroma.
