Transferrin In Korean Children With Attention Deficit Hyperactivity Disorder.
- Author:
Ho Jang KWON
1
;
Myung Ho LIM
;
Mina HA
;
Eun Jung KIM
;
Seung Jin YOO
;
Jong Wan KIM
;
Ki Chung PAIK
Author Information
1. Environmental Health Center, Dankook University Hospital, Cheonan, Korea. paperose@dku.edu
- Publication Type:Original Article
- Keywords:
ADHD;
Transferrin;
Hematology;
Child
- MeSH:
Attention Deficit Disorder with Hyperactivity;
Child;
Diagnostic and Statistical Manual of Mental Disorders;
Erythrocyte Indices;
Ferritins;
Hematology;
Hemoglobins;
Humans;
Iron;
Parents;
Transferrin;
Weights and Measures
- From:Psychiatry Investigation
2011;8(4):366-371
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The aim of the present study was to investigate the relationship between iron, ferritin, transferrin, total iron binding capacity (TIBC), hemoglobin, mean corpuscular volume (MCV) mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in children with ADHD. METHODS: MethodsaaThe sample consisted of 48 ADHD children and sex and age matched control children (a couple of 28 boys, 22 girls; age 6-8 years; mean+/-SD, 6.98+/-0.39). We diagnosed ADHD according to DSM-IV. ADHD symptoms were evaluated subjectively with Conners' Parent Rating Scales, Dupaul Parent ADHD Rating Scales. Subjects with ADHD and control were evaluated the hematology test including the iron, transferrin, MCV etc. Paired t test were used to evaluate the relation of a lot of hematology findings between ADHD and control group. RESULTS: The serum iron, ferritin, transferrin, TIBC, hemoglobin, MCV, MCH, and MCHC of ADHD group were respectively 80.92+/-33.33 ug/dL, 35.81+/-16.59 ng/mL, 248.42+/-44.15 mg/dL, 351.69+/-102.13 ug/dL, 12.78+/-0.71 g/dL, 82.94+/-2.58 fL, 27.18+/-1.12 uug, 32.79+/-1.12%. Otherwise the serum iron, ferritin, transferrin, TIBC, hemoglobin, MCV, MCH, and MCHC of control group were respectively 82.04+/-28.14 ug/dL, 37.05+/-18.28 ng/mL, 266.27+/-25.40 mg/dL, 352.77+/-89.54 ug/dL, 12.77+/-0.70 g/dL, 81.81+/-2.96 fL, 26.69+/-0.99 uug, 32.66+/-0.96%. A significant difference were found in the transferrin(t=2.63, p=0.011), MCV (t=2.19, p=0.034), and MCH (t=2.18, p=0.034). CONCLUSION: These results suggested that lower transferrin levels might be related with ADHD symptoms.
