Electroencephalographic Abnormalities in Clozapine-Treated Patients: A Cross-Sectional Study.
- Author:
Nishant GOYAL
1
;
Samir Kumar PRAHARAJ
;
Pushpal DESARKAR
;
Haque NIZAMIE
Author Information
1. Senior Resident, Centre for Cognitive Neurosciences, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India.
- Publication Type:Brief Communication
- Keywords:
Clozapine;
EEG abnormalities;
Seizures
- MeSH:
Clozapine;
Cross-Sectional Studies;
Electroencephalography;
Humans;
Seizures
- From:Psychiatry Investigation
2011;8(4):372-376
- CountryRepublic of Korea
- Language:English
-
Abstract:
The objective of our study was to examine the electroencephalogram (EEG) abnormalities associated with clozapine treatment. It was a cross-sectional study on 87 psychiatric patients on clozapine treatment. 32 channel digital EEG was recorded and analysed visually for abnormalities. EEG abnormalities were observed in 63.2% of patients. Both slowing and epileptiform activities were noted in 41.4% of patients. The EEG abnormalities were not associated with dose or duration of clozapine exposure.