A Case of Diffuse Dermal Angiomatosis.
- Author:
Joon Hong MIN
1
;
Hyun Min SEO
;
Heun Joo LEE
;
Ji Hye PARK
;
Chong Won CHOI
;
Ga Young LEE
;
Won Serk KIM
Author Information
1. Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. mdcwc@naver.com
- Publication Type:Case Report
- Keywords:
CD31;
Diffuse dermal angiomatosis;
Reactive angioendotheliomatosis
- MeSH:
Angiomatosis;
Dermis;
Endothelial Cells;
Erythrocytes;
Hemangioendothelioma;
Humans;
Lower Extremity;
Male;
Mitosis;
Myofibroblasts;
Skin Neoplasms;
Ulcer;
Vasculitis
- From:Korean Journal of Dermatology
2013;51(2):144-147
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Diffuse dermal angiomatosis is an acquired, benign vascular proliferation with poorly circumscribed, violaceous, and livedoid plaques with frequent ulceration. Histologically, there is diffuse and interstitial proliferation of CD31-positive endothelial cells and myofibroblasts within the dermis. Endothelial atypia, mitoses, and vasculitis are lacking. Here we describe a 52-year-old male who presented with erythematous and purpuric patches on the trunk and lower extremities for 2 years. Histologic examination demonstrated a dense proliferation of endothelial cells in the papillary and reticular dermis. Small vascular spaces and extravasated erythrocytes were noted. Immunohistochemical staining using anti-CD31 antibody was positive.