A Case of CHAP Syndrome.
- Author:
Man Wook SEO
;
Ji Sung KIM
;
Seong Yong YU
;
Byeung Soo SHIN
;
Young Hyun KIM
- Publication Type:Original Article
- Keywords:
Choreoathetosis;
Orofacial dyskinesia;
Hypotonia;
Pseudobular signs
- MeSH:
Anoxia;
Brain;
Heart;
Humans;
Hypothermia;
Movement Disorders;
Muscle Hypotonia;
Nervous System;
Perfusion
- From:Journal of the Korean Geriatrics Society
2001;5(4):348-353
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
CHAP syndorme consists of choreoathetosis, orofacial dyskinesia, affective change, hypotonia, and pseudobulbar signs. CHAP syndrome was firstly des- cribed with onset 1 to 7 days after induced profound hypothermia and complete circulatory arrest for con- genital heart lesion repair. Since then, only a few cases have been reported until now. Case We report a patient who demonstrated all of the elements of the CHAP syndrome in severe cachexic state. Brain SPECT(99mTC-ECD) shows decreased perfusion in left fronto-parieto-temporal lobe. Comments The pathogenesis of CHAP syndrome is obscure. However our case led us to suggest that more essential component pre- disposing to the CHAP syndrome is hypoxia rather than hypothermia. Furthermore, it seems to be related with circulatory insufficiency in extrapyramidal nervous systems.
