A Case of Cryptococcal Meningitis in a Brest Cancer Patient with Liver Metastasis, Suffering from Herpes Zoster.
- Author:
Chul Woo AHN
1
;
Wook Jin CHUNG
;
Beom Seok KIM
;
Se Hang CHO
;
Sun Young RHA
;
Hyun Cheol CHUNG
;
Joo Hang KIM
;
Jae Kyung ROH
;
Byung Soo KIM
;
Hee Jung KIM
;
Kwang Gil LEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cryptococcus meningitis;
Breast cancer
- MeSH:
Amphotericin B;
Breast Neoplasms;
Coma;
Cryptococcosis;
Cryptococcus neoformans;
Drug Therapy;
Female;
Fever;
Herpes Zoster*;
Humans;
Immunity, Cellular;
India;
Ink;
Leukemia;
Liver*;
Lung Diseases;
Lymphoma;
Meningitis, Cryptococcal*;
Middle Aged;
Neoplasm Metastasis*;
Strikes, Employee
- From:Journal of the Korean Cancer Association
1997;29(3):540-540
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cryptococcosis is a relatively common mycosis of human caused by a worldwide Cryptococcus neoformans. Cryptococcosis occurs more frequently in immuno-compromised hosts such as patients with lymphoma, AIDS, leukemia and other debilitating diseases which manifest a condition of altered cell mediated immunity. Also cancer patients with anticancer chemotherapy are at high risk. Cryptococcosis is primarily a pulmonary disease that remains asymptomatic and unrecognised in most cases. Meningitic and meningoencephalitc forms are more frequently diagnosed because of their striking clinical symptoms.Meningoencephalitis is an uncommon form of cryptoccocosis that often leads to coma and death within a short time, if it is not quickly diagnosed and treated properly. The treatment of choice for the cryptococcosis consists of intravenous amphotericin B and 5-fluorocytocine. We report a case of cryptococcal meningitis in 47-year-old female breast cancer patient with liver metastasis after systemic chemotherapy. She complained headach, fever and diagnosed as cryptococcal meningitis after the India ink smear and culture of CSF. After treated with amphotericin B, her conditions were improved.
