A Case of the Treatment in an Adult with Hepatic Undifferentiated (Embryonal) Sarcoma.
- Author:
Kyoung Tae KIM
1
;
Sang Young HAN
;
Eun Hee PARK
;
Jin Seok JANG
;
Myung Hwan ROH
;
Sung Wook LEE
;
Jin Sook JEONG
Author Information
1. Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. syhan@dau.ac.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Sarcoma;
Liver;
Chemotherapy
- MeSH:
Antineoplastic Combined Chemotherapy Protocols/therapeutic use;
Dactinomycin/therapeutic use;
Doxorubicin/therapeutic use;
Female;
Humans;
Ifosfamide/therapeutic use;
Liver Neoplasms/*diagnosis/*drug therapy/pathology;
Middle Aged;
Sarcoma/*diagnosis/*drug therapy/pathology;
Tomography, X-Ray Computed;
Vincristine/therapeutic use
- From:The Korean Journal of Hepatology
2007;13(1):96-102
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Undifferentiated embryonal sarcoma is a rare primary malignant neoplasm of the liver. Undifferentiated sarcoma of the liver in adult is an uncommon hepatic tumor of mesenchymal origin, generally considered an aggressive neoplasm with an unfavorable prognosis. We present a case of undifferentiated sarcoma in a 61-year-old woman. CT scan demonstrated a large heterogenous, exophytic growing hepatic mass in the right lobe with pulmonary metastatic nodules. US guided liver biopsy was done and pathological findings of the liver specimen revealed that isolated or grouped round pleomorphic cells and spindle to stellate cells were present. Immunohistochemical stain showed that tumor cells expressed positivity for vimentin and partially positivity or negativity for cytokeratin. She was diagnosed as having undifferentiated sarcoma of the liver. She received seven courses of VAIA chemotherapy by CWS protocols. Chemotherapy was efficacious and the size of the tumor decreased considerably after the treatment. No tumor recurrence for 12 months is noted.
