Update of the Korean Clinical Practice Guidelines for Endovascular Recanalization Therapy in Patients with Acute Ischemic Stroke.
- Author:
Keun Sik HONG
1
;
Sang Bae KO
;
Kyung Ho YU
;
Cheolkyu JUNG
;
Sukh Que PARK
;
Byung Moon KIM
;
Chul Hoon CHANG
;
Hee Joon BAE
;
Ji Hoe HEO
;
Chang Wan OH
;
Byung Chul LEE
;
Bum Tae KIM
;
Bum Soo KIM
;
Chin Sang CHUNG
;
Byung Woo YOON
;
Joung Ho RHA
Author Information
- Publication Type:Review
- Keywords: Guidelines; Acute ischemic stroke; Large cerebral artery occlusion; Thrombolysis; Reperfusion; Endovascular recanalization therapy
- MeSH: Arteries; Cerebral Arteries; Consensus; Humans; Neuroimaging; Neurosurgeons; Patient Selection; Reperfusion; Stroke*; Tissue Plasminogen Activator; Writing
- From:Journal of the Korean Neurological Association 2016;34(5):297-311
- CountryRepublic of Korea
- Language:Korean
- Abstract: Patients with severe stroke due to acute large cerebral artery occlusion are likely to be severely disabled or die if reperfusion is not achieved in a timely manner. Intravenous tissue plasminogen activator (IV-TPA) administered within 4.5 hours after stroke onset was previously the only proven therapy, but IV-TPA alone does not sufficiently improve the outcome of patients with acute large artery occlusion. With the introduction of the advanced endovascular therapy that enables faster and more successful recanalization, recent randomized trials consecutively and consistently demonstrated the benefit of adding endovascular recanalization therapy (ERT) to IV-TPA. Accordingly, to update the recommendations, we assembled members of a writing committee appointed by the Korean Stroke Society, the Korean Society of Interventional Neuroradiology, and the Society of Korean Endovascular Neurosurgeons. The writing committee revised recommendations based on a review of the accumulated evidence, and a formal consensus was achieved by convening a panel of 34 experts from the participating academic societies. The current guideline provides evidence-based recommendations for ERT in patients with acute large cerebral artery occlusion regarding patient selection, treatment modalities, neuroimaging evaluation, and system organization.