Dominant Dystrophic Epidermolysis Bullosa.
- Author:
Hae Jin LEE
1
;
Ye Jin JUNG
;
Jae Hong KIM
;
Hannah HONG
;
Eung Ho CHOI
Author Information
1. Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea. choieh@yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Dominant dystrophic epidermolysis bullosa;
Epidermolysis bullosa simplex
- MeSH:
Blister;
Cicatrix;
Dermatology;
Electrons;
Epidermolysis Bullosa Dystrophica;
Epidermolysis Bullosa Simplex;
Female;
Foot;
Humans;
Infant
- From:Korean Journal of Dermatology
2010;48(10):889-892
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dystrophic epidermolysis bullosa is a rare, chronic non-inflammatory bullous disease with a hereditary pattern of occurrence, and this disease easily produces bullae that heal with scarring and milium formation. A 13-month-old female baby was brought to the department of dermatology with multiple variable sized bullae and erythematous to dark brownish patches and crusts on both her feet. The histopathologic findings showed subepidermal non-inflammatory blisters and the electron microscopic findings showed vacuolization of the sublamina densa and broken anchoring fibrils. On the basis of the clinical and microscopic findings, she was diagnosed as having dominant dystrophic epidermolysis bullosa. We report here on a case of dominant dystrophic epidermolysis bullosa with the clinical, histological and electron microscopic findings, as well as the family history of the patient.