One-Year Follow-up Pilot Study for Dementia Diagnosis in Elderly with Recall Score of 0 in Korean-version of Mini-Mental State Examination.
10.4235/jkgs.2014.18.1.16
- Author:
Yun Jeong HONG
1
;
Dong Won YANG
;
Bora YOON
;
Yong S SHIM
;
A Hyun CHO
;
Il Woo HAN
;
Myoung Sung MOON
Author Information
1. Department of Neurology, Yong-in Hyoja Geriatric Hospital, Yongin, Korea.
- Publication Type:Original Article
- Keywords:
K-MMSE;
Memory recall;
Enumeration survey;
Dementia
- MeSH:
Aged*;
Alzheimer Disease;
Dementia*;
Demography;
Diagnosis*;
Follow-Up Studies*;
Humans;
Memory;
Mild Cognitive Impairment;
Pilot Projects*;
Reference Values;
Sociology
- From:Journal of the Korean Geriatrics Society
2014;18(1):16-23
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The early stage of Alzheimer disease might show early memory impairment with normal general cognitive function. Our study aimed to investigate elderly with normal Korean version of mini-mental state examination (K-MMSE) score and recall score of 0 for 1 year. We predicted that the patients would show different characteristics and would progress more rapidly compared with normal controls. METHODS: This study was based on the data from complete enumeration survey of Mapo-gu Regional Center for Dementia in 2009. We divided all subjects into three groups: subjects with normal K-MMSE scores and recall score of 0 were group 1-1 (n=152), subjects with abnormal K-MMSE scores were group 1-2 (n=64) and subjects with normal K-MMSE scores and recall score of 1 to 3 were group 1-3 (n=941). We compared basic demographics and social characteristics among the three groups. After 1 year (2010), the subjects in group 1-1 (90 out of 152) underwent follow-up examinations for dementia diagnosis. They were also divided into three groups (2-1, 2-2, 2-3) according to K-MMSE and recall scores. RESULTS: Group 1-1 showed different baseline characteristics compared with normal controls. After 1 year, 25.5% (23 out of 90) of the group 2-1 were diagnosed as mild cognitive impairment (n=16) or dementia (n=7). CONCLUSION: Our study suggested that subjects with normal K-MMSE scores but recall score of 0 are not entirely "normal". Further detailed evaluation might be needed if memory impairment is suspicious although the K-MMSE scores are within normal range.