Miliary Tuberculosis Involving the Central Nervous System.
- Author:
Tae Whoan LEE
1
;
Hun Joo KIM
;
Chul HU
;
Yong Pyo HAN
;
Soon Ki HONG
;
Jhin Soo PYEN
;
Myung Soon KIM
;
Mee Yon CHO
;
Yoon Mee KIM
Author Information
1. Department of Neurosurgery, Wonju College of Medicine, Yonsei University, Wonju, Korea.
- Publication Type:Original Article
- Keywords:
Miliary cerebral tuberculosis;
Small enhancing nodule;
Mycobacterium tuberculosis
- MeSH:
Biopsy;
Brain;
Central Nervous System*;
Ethambutol;
Female;
Granuloma;
Headache;
Humans;
Isoniazid;
Magnetic Resonance Imaging;
Military Personnel;
Mycobacterium tuberculosis;
Necrosis;
Prednisolone;
Prevalence;
Pyrazinamide;
Rifampin;
Tuberculoma;
Tuberculosis;
Tuberculosis, Miliary*;
Tuberculosis, Pulmonary;
Young Adult
- From:Journal of Korean Neurosurgical Society
1996;25(11):2354-2359
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In recent times, central nervous system(CNS) tuberculosis has been rare and the prevalence of the focal form, the tuberculoma, varies from 1 per 20 to 1 per 1000. CNS tuberculosis occurs as a result of hematogenous sparead from a primary focus, mostly pulmonary tuberculosis. It can be diffuse exudative leptomeningitis or a localized tuberculoma; the former is more common. We report a case of military cerebral tuberculosis in a 24-year-old female who had been having headaches for 4 months. Magnetic resonance imaging showed numerous small round Gadolinium-enhanced supratentorial and infratentorial lesions scattered throughtout the brain. Histologic examination confirmed well-defined tuberculous granulomas with central caseous necrosis in open biopsy, containing several acid-fast bacilli, the patient was treated with isoniazid, rifampin, ethambutol, pyrazinamide in combination with prednisolone.
