A Granular Cell Tumor Located in the Gastric Cardia.
- Author:
Jin Sup PARK
1
;
Gwang Ha KIM
;
Mi Ra KIM
;
Hong Ryul JEONG
;
Jae Hoon CHEONG
;
Chan Ho PARK
;
Sun Mi LEE
;
Tae Oh KIM
;
Jeong HEO
;
Dae Hwan KANG
;
Geun Am SONG
;
Mong CHO
Author Information
1. Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. doc0224@chol.com
- Publication Type:Case Report
- Keywords:
Granular cell tumor;
Gastric cardia;
Endoscopic mucosal resection
- MeSH:
Adult;
Breast;
Cardia;
Connective Tissue;
Endoscopy;
Endosonography;
Esophagus;
Female;
Granular Cell Tumor;
Humans;
Mucous Membrane;
S100 Proteins;
Skin
- From:Korean Journal of Gastrointestinal Endoscopy
2008;36(1):22-26
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
First described in 1926 by Abrikossoff, a granular cell tumor is a benign lesion and commonly involves the skin, connective tissue, and breast, but rarely the esophagus. The origin of granular cell tumors is controversial. The tumor is thought to arise from a Schwann cell origin, based on characteristics such as the positive expression of S-100 protein determined by immunohistochemical staining. A 29-year-old female was referred from the local clinic because of a polypoid lesion in the gastric cardia. After performing endoscopy and endoscopic ultrasonography, a 1.5 cm submucosal tumor covered with normal mucosa was found in the gastric cardia. Endoscopic mucosal resection revealed a tumor that initiated in the esophagus, and grew into the cardia. Immunohistochemical analysis revealed strong positive staining for S-100 protein, confirming the presence of a granular cell tumor.
