A Case of palisaded, Encapsulated Neuroma.
- Author:
Seok Jin HONG
;
Sam Hyeong KIM
;
Hoon KANG
;
Sook Ja SON
;
Hee Jin JANG
- Publication Type:Case Report
- Keywords:
Palisaded;
Encapsulated neuroma
- MeSH:
Basophils;
Dermis;
Female;
Humans;
Korea;
Middle Aged;
Mucin-1;
Neuroma*;
S100 Proteins;
Telangiectasis
- From:Korean Journal of Dermatology
1998;36(1):173-176
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Palisaded, encapsulated neuroma is characterized clinically by a solitary, slowly-growing and dome-shaped papule or nodule, usually accompanied by telangiectasia on the surface, and histopathologically by an encapsulated nodule in the dermis and the palisading arrangement of nuclei. A 57-year-old female patient presented with a 1cm-sized, solitary nodule on the right ala nasi which had been present for about 5 years. The nodule had a tendency to slow growth and it became a polypoid nodule. Telangiectasia was shown on the surface of the lesion. Histopathlogical findings showed a well-defined and encapsulated nodule in the dermis, composed of spindle cells with basophilic and plump nuclei in a palisading fashion. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein, while the capsule of the nodule was negative for S-100 protein. Epithelial membrane antigens were focally positive only on the capsule of the nodule. We report herein a case of palisaded, encapsulated neuroma, one case of which has been reported in Korea.
