The impact of malnutrition on survival in patients with gynecologic cancer undergoing chemotherapy.
10.4163/jnh.2017.50.6.595
- Author:
Ju Hee NHO
1
;
Yong Soon KWON
;
Seongil JO
Author Information
1. College of Nursing, Chonbuk National University, Jeonju 54899, Korea.
- Publication Type:Original Article
- Keywords:
gynecologic neoplasm;
malnutrition;
survival;
chemotherapy
- MeSH:
Depression;
Drug Therapy*;
Female;
Genital Neoplasms, Female;
Humans;
Korea;
Malnutrition*;
Nutrition Assessment;
Nutritional Status;
Observational Study;
Prospective Studies;
Survivors;
Tertiary Care Centers
- From:Journal of Nutrition and Health
2017;50(6):595-602
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Malnutrition is a major concern in patients with gynecologic cancer receiving chemotherapy. The aim of this study was to evaluate the prognostic significance of malnutrition in patients with gynecologic cancer undergoing chemotherapy. METHODS: A prospective, observational study was conducted on a total of 99 subjects who were treated at a tertiary hospital in Korea. Data regarding demographic, clinical, nutritional, and psychological characteristics at baseline and survival were obtained. RESULTS: Performance status, nutritional status, depression, and annual income were significantly different between survivors and non-survivors. Multivariate Cox modeling after adjusting for other factors showed that a malnourished status in patients with gynecologic cancer undergoing chemotherapy was a significant and independent negative influencing factor for survival. CONCLUSION: These findings provide evidence that adequate nutritional assessment and intervention may assist in improving survival in patients with gynecologic cancer undergoing chemotherapy.
