Familial cold urticaria.
- Author:
Jae Bok JUN
;
Sang Lip CHUNG
- Publication Type:Original Article
- Keywords:
Familial cold urticaria;
Family history;
Leukocytosis
- MeSH:
Adult;
Arthralgia;
Biopsy;
Blood Sedimentation;
Chills;
Cryopyrin-Associated Periodic Syndromes*;
Eosinophils;
Fever;
Headache;
Humans;
Leukocytosis;
Lymphocytes;
Male;
Neutrophils;
Pedigree;
Weather;
Wills
- From:Korean Journal of Dermatology
1993;31(1):87-91
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case of familial cold urticaria is reported in a 29-year-old male who showed generalized erythematous macules and papules, finally an urticarial eruption shortly after cold exposure, particularly in cold windy weather with damp. Coincidentally, systemic symptoms such as headache, fever and chills, arthralgia, and conjunctival injection were acompanied. Autosomal dominant inheritance was found on examination of his pedigree in which 11 of 18 rnembers showed similar clinical manifestations. Routme laboratory findings were within normal limits except mild leukocytosis and elevated erythrocyte sedimentation rate. Biopsy specimen from a cold-evoked lesion revealed mild ederna and mild perivascular infiltrations composed of neutrophils, eosinophils and lymphocytes in the derms, Treatments included several widely-used antihistaminics, but turned out to be unsatisfactory.
